ncRNA name | hsa-miR-219-5p |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human RPE cells |
Methods | RT-PCR, MTT assay, flow cytometry, dual‑luciferase reporter assay, Western blot |
Expression pattern | up-regulated |
Functional description | miR-219-5p was involved in the progression of DR through regulating human RPE cell apoptosis by modulation of the LRH-1/Wnt/β-Catenin signaling pathway. |
PubMed ID | 29749515 |
Year | 2018 |
Title | Significant role of microRNA‑219‑5p in diabetic retinopathy and its mechanism of action. |
Drug-related ncRNA | NO |
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